Chromatin deregulation in disease
نویسندگان
چکیده
منابع مشابه
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Malignancies are characterized by the reprogramming of epigenetic patterns. This reprogramming includes gains or losses in DNA methylation and disruption of normal patterns of covalent histone modifications, which are associated with changes in chromatin remodeling processes. This review will focus on the mechanisms underlying this reprogramming and, specifically, on the role of histone modific...
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ژورنال
عنوان ژورنال: Chromosoma
سال: 2015
ISSN: 0009-5915,1432-0886
DOI: 10.1007/s00412-015-0530-0